Description

Lobetyolin CAS NO 136085-37-5 is a bioactive natural product and a polyacetylene glycoside isolated from various medicinal plants, notably from the *Codonopsis* genus. This compound is of significant interest for its potential pharmacological properties, making it a valuable reference standard and research chemical. It is primarily sought after by researchers and manufacturers in the pharmaceutical, nutraceutical, and biotechnology sectors for drug discovery, quality control of herbal extracts, and biochemical studies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the qualitative and quantitative analysis of herbal medicines and dietary supplements containing *Codonopsis* species.
• Biomedical Research: Serves as a key investigational compound in pharmacological studies targeting its reported anti-inflammatory, immunomodulatory, and neuroprotective activities.
• Natural Product Chemistry: Employed as a building block or intermediate in the synthesis of novel derivatives for structure-activity relationship (SAR) studies.
• Quality Control (QC) in Herbal Industry: Essential for HPLC and LC-MS methods to standardize and authenticate extracts of *Codonopsis pilosula* (Dangshen) and related botanicals, ensuring product consistency and efficacy.
• Academic Research: Utilized in universities and research institutes for studies in phytochemistry, pharmacognosy, and metabolic pathway analysis.

Basic Information

Product Name	Lobetyolin
CAS No.	136085-37-5
Molecular Formula	C₂₀H₂₈O₈
Molecular Weight	396.43 g/mol
Synonyms	Lobetyolin; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethynyl]tetrahydro-2H-pyran-3,4,5-triol; 4-[2-[(2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]phenol; Polyacetylene glucoside from Codonopsis pilosula
EINECS	Contact for details

Quality Control

Our Lobetyolin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data on identity, purity, and impurities is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.