Description

tert-Butyl1-Mercapto-3-Phenylpropan-2-Ylcarbamate is a specialized carbamate derivative featuring both a tert-butyloxycarbonyl (Boc) protecting group and a thiol (mercapto) functionality. This compound is a valuable building block and intermediate in advanced organic synthesis, particularly in the pharmaceutical and agrochemical sectors. Its structure makes it essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where controlled introduction of a protected thiol group is required.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting cardiovascular or neurological diseases.
• Peptide Chemistry: Used in the solid-phase and solution-phase synthesis of peptides and peptidomimetics, where the Boc group offers orthogonal protection.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific modes of action.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating complex molecular architectures.
• Ligand and Catalyst Preparation: Useful for preparing specialized ligands for metal catalysis or as a component in chiral auxiliaries.

Basic Information

Product Name	tert-Butyl1-Mercapto-3-Phenylpropan-2-Ylcarbamate
CAS No.	135949-98-3
Molecular Formula	C14H21NO2S
Molecular Weight	267.39 g/mol
Synonyms	tert-Butyl (1-mercapto-3-phenylpropan-2-yl)carbamate; 2-[(tert-Butoxycarbonyl)amino]-3-phenylpropane-1-thiol; Boc-Cys(Ph)-OH thiol derivative; N-Boc-β-phenylcysteamine; 1-Mercapto-3-phenyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propane; (1-Mercapto-3-phenylpropan-2-yl)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-β-phenylcysteamine
EINECS	Contact for details

Quality Control

Our tert-Butyl1-Mercapto-3-Phenylpropan-2-Ylcarbamate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.