Description

(R)-(-)-2-(2-Isoindolinyl)Butan-1-Ol CAS NO 135711-18-1 is a chiral isoindoline derivative, a high-value building block in asymmetric synthesis. Its primary commercial value lies in its utility as a key chiral intermediate for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereoisomer can enhance efficacy and reduce environmental impact.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling reactions).
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new chiral methodologies and constructing complex molecular architectures.
• Process Chemistry: Integrated into scalable manufacturing routes for optically active compounds, supporting process development and optimization.

Basic Information

Product Name	(R)-(-)-2-(2-Isoindolinyl)Butan-1-Ol
CAS No.	135711-18-1
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	(R)-2-(Isoindolin-2-yl)butan-1-ol; (R)-(-)-2-(2-Isoindolinyl)-1-butanol; (2R)-2-(1,3-Dihydro-2H-isoindol-2-yl)butan-1-ol; (R)-2-(1,3-Dihydroisoindol-2-yl)butan-1-ol; (R)-2-(Isoindolin-2-yl)-1-butanol; (R)-2-(2-Isoindolinyl)butanol; (R)-2-Isoindolin-2-yl-butan-1-ol
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-(2-Isoindolinyl)Butan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.