Description

1-Furan-2-Yl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its unique fused-ring structure containing both tetrahydroisoquinoline and furan moieties makes it a valuable scaffold for pharmaceutical research and fine chemical manufacturing. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the privileged tetrahydroisoquinoline scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the furan ring can contribute to specific biological activity and binding properties.
• Ligand and Catalyst Development: Serves as a precursor or core structure for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, leveraging its conjugated system.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for library synthesis and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: A versatile intermediate for creating complex, high-value specialty chemicals used in flavors, fragrances, and advanced polymers.

Basic Information

Product Name	1-Furan-2-Yl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	135675-29-5
Molecular Formula	C₁₃H₁₃NO
Molecular Weight	199.25 g/mol
Synonyms	1-(Furan-2-yl)-1,2,3,4-tetrahydroisoquinoline; 2-(1,2,3,4-Tetrahydroisoquinolin-1-yl)furan; 1-(2-Furyl)-1,2,3,4-tetrahydroisoquinoline; Furan-2-yl-tetrahydroisoquinoline; 1-(2-Furanyl)-1,2,3,4-tetrahydro-isoquinoline; 1,2,3,4-Tetrahydro-1-(2-furanyl)isoquinoline; 135675-29-5
EINECS	Contact for details

Quality Control

Our 1-Furan-2-Yl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific grade requirements (e.g., >98%, >99%), please contact our technical team to discuss your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.