Description

1,2-Cyclobutanediol,3,4-Dichloro-,(1Alpha,2Alpha,3Beta,4Beta)-(9Ci) is a high-purity, stereochemically defined chlorinated cyclobutane derivative. This compound serves as a critical chiral building block and advanced intermediate for the synthesis of complex pharmaceutical molecules and specialty agrochemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-opening and functionalization reactions.
• Fine Chemical Production: Intermediate for the manufacture of other high-value, stereochemically complex specialty chemicals.

Basic Information

Product Name	1,2-Cyclobutanediol,3,4-Dichloro-,(1Alpha,2Alpha,3Beta,4Beta)-(9Ci)
CAS No.	135559-05-6
Molecular Formula	C4H6Cl2O2
Molecular Weight	157.00 g/mol
Synonyms	(1α,2α,3β,4β)-3,4-Dichlorocyclobutane-1,2-diol; 3,4-Dichloro-1,2-cyclobutanediol (stereoisomer); cis-3,4-Dichlorocyclobutane-1,2-diol; (1R,2R,3S,4S)-3,4-Dichlorocyclobutane-1,2-diol; 1,2-Cyclobutanediol, 3,4-dichloro-, (1R,2R,3S,4S)-; 135559-05-6; Cyclobutane-1,2-diol, 3,4-dichloro-, (1α,2α,3β,4β)-
EINECS	Contact for details

Quality Control

Every batch of 1,2-Cyclobutanediol,3,4-Dichloro-,(1Alpha,2Alpha,3Beta,4Beta)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.