Description

5-Amino-1-Ethyl-3,3-Dimethyl-2,3-Dihydro-1H-Indol-2-One is a high-purity, synthetically versatile indolinone derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex heterocyclic compounds with targeted biological activity. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct fused ring systems and other sophisticated molecular architectures.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional organic materials.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized indole-based colorants.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	5-Amino-1-Ethyl-3,3-Dimethyl-2,3-Dihydro-1H-Indol-2-One
CAS No.	135437-78-4
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	5-Amino-1-ethyl-3,3-dimethylindolin-2-one; 1-Ethyl-5-amino-3,3-dimethyl-2-indolinone; 2H-Indol-2-one, 5-amino-1-ethyl-1,3-dihydro-3,3-dimethyl-; 5-Amino-1-ethyl-3,3-dimethyl-2-oxindole; 135437-78-4; AE-DDIO; 3,3-Dimethyl-5-amino-1-ethyl-2-indolinone
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Ethyl-3,3-Dimethyl-2,3-Dihydro-1H-Indol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.