Description

Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, especially tropane alkaloid derivatives.
• Neurological Drug Research: Serves as a core scaffold for the development of potential treatments for neurological disorders, including Parkinson's disease and depression.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to create enantiomerically pure compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic
CAS No.	135416-43-2
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane-2-carboxylic acid; 2-Carboxy-8-azabicyclo[3.2.1]octane; Tropane-2-carboxylic acid; Nortropane-2-carboxylic acid; 8-Nor-3α-tropanecarboxylic acid; Endo-8-Azabicyclo[3.2.1]octane-2-carboxylic acid; (1R,2S,5S)-8-Azabicyclo[3.2.1]octane-2-carboxylic acid (for specific enantiomer); Caindexname
EINECS	Contact for details

Quality Control

Our Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, supporting regulatory filings for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0% (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.