Description

8-Hydroxy-3,4-Dihydro-2H-Isoquinolin-1-One is a high-purity heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its unique isoquinolinone core structure makes it a valuable precursor for developing novel pharmaceuticals and functional materials. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its privileged isoquinolinone scaffold.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor in complex organic transformations, including cyclization and functionalization reactions.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and advanced organic materials with specific electronic or optical properties.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and the exploration of new chemical entities.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in related chemical production.

Basic Information

Product Name	8-Hydroxy-3,4-Dihydro-2H-Isoquinolin-1-One
CAS No.	135329-20-3
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	8-Hydroxy-1,2,3,4-tetrahydroisoquinolin-1-one; 1(2H)-Isoquinolinone, 3,4-dihydro-8-hydroxy-; 8-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone; 8-Hydroxy-1,2,3,4-tetrahydro-1-isoquinolinone; 8-Hydroxy-1-oxo-1,2,3,4-tetrahydroisoquinoline; 135329-20-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-3,4-Dihydro-2H-Isoquinolin-1-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets exacting research and industrial-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.