Description

2-[(tert-Butylamino)Carbonyl]Thiophene-3-Carboxylic Acid is a high-purity, specialized organic building block featuring a thiophene core functionalized with a carboxylic acid and a tert-butylaminocarbonyl group. This compound matters as a critical intermediate in advanced pharmaceutical synthesis and agrochemical research, enabling the construction of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing more complex heterocyclic compounds and functionalized thiophene derivatives in academic and industrial labs.
• Material Science Research: Investigated for use in the development of organic semiconductors, conductive polymers, and other specialty electronic materials due to the thiophene moiety.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-[(tert-Butylamino)Carbonyl]Thiophene-3-Carboxylic Acid
CAS No.	135278-56-7
Molecular Formula	C10H13NO3S
Molecular Weight	227.28 g/mol
Synonyms	3-Thiophenecarboxylic acid, 2-[[(1,1-dimethylethyl)amino]carbonyl]-; 2-[(tert-Butylcarbamoyl)]thiophene-3-carboxylic acid; 2-(tert-Butylcarbamoyl)thiophene-3-carboxylic acid; 2-(N-tert-Butylaminocarbonyl)thiophene-3-carboxylic acid; 2-(tert-Butylaminocarbonyl)-3-thiophenecarboxylic acid; 2-(tert-Butylcarbamoyl)-3-thiophenecarboxylic acid; 135278-56-7; tert-Butyl 3-carboxythiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our 2-[(tert-Butylamino)Carbonyl]Thiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.