Description

(E)-3-(6-Bromo-1H-Indol-3-Yl)Acrylic Acid is a high-purity, synthetically valuable indole derivative featuring a bromo-substituted aromatic ring conjugated to an acrylic acid moiety. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing novel pesticides and herbicides with specific biological activity.
• Organic Synthesis: Versatile reagent for constructing complex heterocyclic systems and conjugated molecular frameworks via cross-coupling and cyclization reactions.
• Material Science: Monomer or precursor for functional polymers and organic electronic materials due to its conjugated π-system.
• Biochemical Research: Used in the study of enzyme inhibitors and as a probe in biochemical assays.
• Academic & R&D: Essential compound for methodological development and discovery chemistry in university and industrial laboratories.

Basic Information

Product Name	(E)-3-(6-Bromo-1H-Indol-3-Yl)Acrylic Acid
CAS No.	135250-41-8
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	(E)-3-(6-Bromo-1H-indol-3-yl)-2-propenoic acid; 6-Bromo-3-indolylacrylic acid; trans-3-(6-Bromo-1H-indol-3-yl)acrylic acid; (E)-3-(6-Bromoindol-3-yl)acrylic Acid; 2-Propenoic acid, 3-(6-bromo-1H-indol-3-yl)-, (E)-; 6-Bromotryptophol acrylic acid derivative; 135250-41-8; 6-Bromoindole-3-acrylic acid
EINECS	Contact for details

Quality Control

Our (E)-3-(6-Bromo-1H-Indol-3-Yl)Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.