Description

3-Benzyloxy-2,3,3A,7A-Tetrahydrobenzothiophen-5-(4H)-One-1,1-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfone and benzyl-protected heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise stereochemistry and functional group compatibility are paramount. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary drug candidates and complex molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Organic Synthesis Reagent: Employed in constructing complex heterocyclic frameworks and sulfone-containing compounds for various chemical applications.

Basic Information

Product Name	3-Benzyloxy-2,3,3A,7A-Tetrahydrobenzothiophen-5-(4H)-One-1,1-Dioxide
CAS No.	135138-42-0
Molecular Formula	C15H16O4S
Molecular Weight	292.35 g/mol
Synonyms	3-Benzyloxy-2,3,3a,7a-tetrahydro-5H-benzothiophen-5-one 1,1-dioxide; 3-Benzyloxy-2,3,3a,7a-tetrahydrobenzothiophene-5(4H)-one 1,1-dioxide; 5H-Benzothiophen-5-one, 2,3,3a,7a-tetrahydro-3-(phenylmethoxy)-, 1,1-dioxide; 3-(Benzyloxy)-2,3,3a,7a-tetrahydro-5H-benzothiophen-5-one 1,1-dioxide
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-2,3,3A,7A-Tetrahydrobenzothiophen-5-(4H)-One-1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.