Description

4-(Aminosulfonyl)Thiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the simultaneous presence of a carboxylic acid and a sulfonamide group on a thiophene scaffold, enabling diverse derivatization for creating novel molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates. Its structural features make it a valuable precursor for developing compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting enzymes where the sulfonamide moiety can act as a pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Synthesis Reagent: Employed in organic chemistry research for constructing complex heterocyclic systems and for introducing both acidic and sulfonamide functionalities.
• Ligand Synthesis: Useful for preparing chelating ligands in coordination chemistry and catalysis due to its multiple donor atoms.

Basic Information

Product Name	4-(Aminosulfonyl)Thiophene-2-Carboxylic Acid
CAS No.	135080-31-8
Molecular Formula	C5H5NO4S2
Molecular Weight	207.23 g/mol
Synonyms	2-Carboxy-4-sulfamoylthiophene; 4-Sulfamoylthiophene-2-carboxylic acid; Thiophene-2-carboxylic acid, 4-(aminosulfonyl)-; 4-Sulfamoyltiophene-2-carboxylic Acid; 2-Thiophenecarboxylic acid, 4-(aminosulfonyl)-; 4-Sulfamoyl-2-thiophenecarboxylic acid; 4-Sulfamoylthiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-(Aminosulfonyl)Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and stored under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.