Description

Ethyl 2-Dimethylamino-4-Trifluoromethyl-5-Thiazolecarboxylate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in life sciences, offering a unique trifluoromethyl-substituted thiazole core that imparts desirable physicochemical properties to target molecules. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry programs targeting CNS, anti-infective, and anti-inflammatory therapies.
• Agrochemical Synthesis: Serves as a crucial building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Research: Used in the synthesis of advanced organic materials, including liquid crystals, organic semiconductors, and polymers with specific electronic or optical properties.
• Chemical Biology & Proteomics: Employed as a reactive handle or tagging agent in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs serving the global pharmaceutical and agrochemical industries.

Basic Information

Product Name	Ethyl 2-Dimethylamino-4-Trifluoromethyl-5-Thiazolecarboxylate
CAS No.	135026-10-7
Molecular Formula	C9H11F3N2O2S
Molecular Weight	268.26 g/mol
Synonyms	Ethyl 2-(dimethylamino)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-(dimethylamino)-4-(trifluoromethyl)-, ethyl ester; 2-Dimethylamino-4-trifluoromethylthiazole-5-carboxylic acid ethyl ester; Ethyl 2-(N,N-dimethylamino)-4-trifluoromethyl-5-thiazolecarboxylate; 135026-10-7; 4-Trifluoromethyl-2-dimethylaminothiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Dimethylamino-4-Trifluoromethyl-5-Thiazolecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.