Description

2-Thiazolemethanol, α-Methyl-, (Alphar)- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific stereochemistry is crucial for biological activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create novel, high-value molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where specific stereoisomers enhance efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of complex molecules for electronic chemicals, flavors, and fragrances research.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new reaction development and stereochemistry research.

Basic Information

Product Name	2-Thiazolemethanol, α-Methyl-, (Alphar)- (9Ci)
CAS No.	134932-60-8
Molecular Formula	C5H7NOS
Molecular Weight	129.18 g/mol
Synonyms	(αR)-α-Methyl-2-thiazolemethanol; (R)-(-)-α-Methyl-2-thiazolemethanol; (R)-α-Methylthiazole-2-methanol; (R)-2-(1-Hydroxyethyl)thiazole; Alphar-Methyl-2-thiazolemethanol; (R)-2-(1-Hydroxyethyl)-1,3-thiazole; (R)-HET
EINECS	Contact for details

Quality Control

Our 2-Thiazolemethanol, α-Methyl-, (Alphar)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.