Description

(3S)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its stereochemically defined tetrahydroisoquinoline core is a privileged scaffold in medicinal chemistry, enabling the development of targeted bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in advanced synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of potential drug candidates targeting neurological disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective reactions to create enantiomerically pure compounds.
• Agrochemical Development: Building block for novel active ingredients in crop protection and pesticide formulations.
• Fine Chemical Synthesis: Intermediate in the multi-step production of complex organic molecules for specialty applications.
• Academic & R&D: Used in university and institutional laboratories for methodological development and biochemical studies.

Basic Information

Product Name	(3S)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide
CAS No.	134732-98-2
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxamide; (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxamide; L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid amide; (S)-Tic-NH2; (3S)-THIQ-3-Carboxamide; (S)-THIQ-CONH2; (S)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our (3S)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.