Description

Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-5-Yl-, 1,1-Dimethylethyl Ester is a specialized bicyclic carbamate derivative, serving as a critical advanced pharmaceutical intermediate and chiral building block in organic synthesis. Its unique 3-azabicyclo[4.1.0]heptane scaffold makes it invaluable for constructing complex molecular architectures with precise stereochemistry. This high-purity compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Chiral Synthesis: Utilized as a stereodefined building block for the asymmetric synthesis of complex natural products and bioactive molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry: Serves as a starting material or intermediate in scalable GMP manufacturing processes for clinical trial materials.
• Agrochemical Development: Potential intermediate for creating novel pesticides and herbicides with specific activity profiles.
• Academic & Industrial R&D: Used in methodological development and catalysis research within organic chemistry laboratories.

Basic Information

Product Name	Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-5-Yl-, 1,1-Dimethylethyl Ester
CAS No.	134677-64-8
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	tert-Butyl 3-azabicyclo[4.1.0]heptane-5-carboxylate; 3-Azabicyclo[4.1.0]heptane-5-carboxylic acid, 1,1-dimethylethyl ester; 5-(tert-Butoxycarbonyl)-3-azabicyclo[4.1.0]heptane; BOC-3-azabicyclo[4.1.0]heptane-5-carboxylate; 3-Azabicyclo[4.1.0]heptane-5-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 3-azabicyclo[4.1.0]hept-5-ylcarbamate; BOC-protected 3-azabicyclo[4.1.0]heptane-5-amine derivative
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, 3-Azabicyclo[4.1.0]Hept-5-Yl-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.