Description

2H-Pyrrole-2-Carboxamide,3,4-Dihydro-4-Mercapto-(9Ci) is a specialized heterocyclic building block featuring a unique pyrrole core with a reactive mercapto group. This compound matters for its role as a critical intermediate in the synthesis of complex pharmaceuticals and advanced organic materials, enabling the introduction of sulfur-containing functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for developing conductive polymers, organic semiconductors, and advanced polymeric materials.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the study of protein interactions due to the thiol group.
• Catalyst Ligand Development: Acts as a precursor for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Item	Details
Product Name	2H-Pyrrole-2-Carboxamide,3,4-Dihydro-4-Mercapto-(9Ci)
CAS No.	134642-84-5
Molecular Formula	C5H8N2OS
Molecular Weight	144.19 g/mol
Synonyms	4-Mercapto-3,4-dihydro-2H-pyrrole-2-carboxamide; 3,4-Dihydro-4-mercapto-2H-pyrrole-2-carboxamide; 4-Thiol-3,4-dihydro-2H-pyrrole-2-carboxylic acid amide; 4-Sulfanyl-3,4-dihydro-2H-pyrrol-2-carboxamide; Dihydro-4-mercaptopyrrole-2-carboxamide; 2H-Pyrrole-2-carboxamide, 3,4-dihydro-4-mercapto-; 4-Mercaptodihydropyrrole-2-carboxamide
EINECS	Contact for details

Quality Control

Our 2H-Pyrrole-2-Carboxamide,3,4-Dihydro-4-Mercapto-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.