Description

6-Fluoro-1-Methyl-1H-Indole-2,3-Dione is a high-purity, fluorinated isatin derivative, a crucial heterocyclic building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile precursor for developing novel pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated indole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioactivity and metabolic stability.
• Organic Synthesis Building Block: Serves as a versatile precursor for complex heterocycles, including quinolones, pyrroloquinolines, and other fused ring systems.
• Material Science Precursor: Potential use in synthesizing organic semiconductors, dyes, and photoactive materials due to the electron-withdrawing isatin core.
• Biochemical Probe Development: Utilized in medicinal chemistry to create fluorinated probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	6-Fluoro-1-Methyl-1H-Indole-2,3-Dione
CAS No.	134640-74-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	6-Fluoro-1-methylisatin; 1-Methyl-6-fluoroisatin; 6-Fluoro-1-methyl-1H-indole-2,3-dione; 6-Fluoro-1-methyl-2,3-dihydro-1H-indole-2,3-dione; 2,3-Dihydro-6-fluoro-1-methyl-1H-indole-2,3-dione; 6-Fluoro-1-methylindoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1-Methyl-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.