Description

Pyridine, 2-[(1,1-Dimethylethyl)dimethylsilyl]- (9Ci) is a specialized organosilicon-protected pyridine derivative, a crucial building block in advanced organic synthesis. Its core value lies in providing a sterically hindered, silicon-based protecting group for the pyridine nitrogen, enabling selective reactions in complex molecule construction. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of complex drug candidates, particularly in nucleoside and heterocyclic chemistry.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where selective protection/deprotection strategies are required.
• Ligand Precursor: Serves as a precursor for sophisticated nitrogen-containing ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials where the pyridine moiety is integral.
• Process Chemistry: Enables scalable, multi-step synthetic routes in fine chemical production by protecting reactive sites.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis laboratories.

Basic Information

Product Name	Pyridine, 2-[(1,1-Dimethylethyl)dimethylsilyl]- (9Ci)
CAS No.	134435-17-9
Molecular Formula	C11H19NSi
Molecular Weight	193.36 g/mol
Synonyms	2-(tert-Butyldimethylsilyl)pyridine; 2-TBDMS-Pyridine; 2-(tert-Butyl(dimethyl)silyl)pyridine; N-TBDMS-2-Pyridine; Pyridine, 2-[(1,1-dimethylethyl)dimethylsilyl]-; 2-Pyridyl-tert-butyldimethylsilane; 2-(tert-Butyldimethylsilyl)pyridine; tert-Butyldimethyl(2-pyridyl)silane
EINECS	Contact for details

Quality Control

Our Pyridine, 2-[(1,1-Dimethylethyl)dimethylsilyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.