Description

2-Amino-Indan-2-Carboxylic Acid Methyl Ester is a specialized chiral amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique indane scaffold and functional groups make it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, neurological agents, and other therapeutic candidates.
• Peptidomimetics Research: Used to construct conformationally constrained peptide analogs for drug discovery and biochemical studies.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents.
• Academic & Industrial R&D: Employed in methodological development and the exploration of new chemical spaces in both academic and corporate laboratories.

Basic Information

Product Name	2-Amino-Indan-2-Carboxylic Acid Methyl Ester
CAS No.	134425-84-6
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	2-Aminoindane-2-carboxylic acid methyl ester; Methyl 2-aminoindane-2-carboxylate; 2-Amino-2-indancarboxylic acid methyl ester; (2-Amino-1,3-dihydro-2H-inden-2-yl)methyl ester; 2-Amino-2H-indene-2-carboxylic acid methyl ester; 2-Amino-2-indanecarboxylic acid methyl ester; Methyl 2-amino-2-indancarboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-Indan-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and advanced research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.