Description

4-Bromochlorobenzene-D4 is a deuterated aromatic compound, specifically a benzene ring substituted with bromine, chlorine, and four deuterium atoms. This stable isotope-labeled analog is essential for applications requiring precise internal standards and tracer studies, providing unmatched accuracy in quantitative analysis. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, isotopically labeled intermediates.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference standard in GC-MS and LC-MS analysis for method development and validation.
• Metabolic Pathway Tracing: Used in pharmaceutical and agrochemical research to study the absorption, distribution, metabolism, and excretion (ADME) of parent compounds.
• Deuterated Pharmaceutical Intermediate: Acts as a building block in the synthesis of deuterated drug candidates, which can offer improved metabolic stability and pharmacokinetic profiles.
• NMR Spectroscopy Solvent & Reagent: Employed as a deuterated solvent or reagent in nuclear magnetic resonance (NMR) studies to avoid signal interference.
• Environmental Fate Studies: Utilized as a tracer to monitor the degradation and environmental behavior of bromochlorobenzene derivatives.
• Chemical Reaction Mechanism Studies: Provides insights into reaction kinetics and mechanisms by tracing the fate of specific atoms within a molecule.

Basic Information

Product Name	4-Bromochlorobenzene-D4
CAS No.	134415-42-2
Molecular Formula	C6D4BrCl
Molecular Weight	195.48 g/mol
Synonyms	1-Bromo-4-chlorobenzene-D4; p-Bromochlorobenzene-D4; 4-Chlorobromobenzene-D4; 1-Chloro-4-bromobenzene-D4; (2,3,5,6-2H4)-4-Bromochlorobenzene; Deuterated p-Bromochlorobenzene; Bromo(chloro-2H4)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromochlorobenzene-D4 is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR, GC-MS, and HPLC, to verify chemical and isotopic purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, isotopic enrichment (D-atom %), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.