Description

T-Butyl-Dimethylsilyl-(3-Propionylphenol) is a high-purity, organosilicon-protected phenolic intermediate of significant importance in advanced organic synthesis. Its primary value lies in serving as a key building block for the construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and agrochemical industries who require a reliable and consistent source of specialized synthetic precursors.

Application

• Pharmaceutical Intermediate: A crucial protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with phenolic functionalities.
• Organic Synthesis Building Block: Used in coupling reactions, such as Suzuki or Heck cross-couplings, where the silyl group acts as a protective moiety for the phenol.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential use in the synthesis of specialized monomers for advanced polymers and functional materials.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in university and corporate research settings.

Basic Information

Product Name	T-Butyl-Dimethylsilyl-(3-Propionylphenol)
CAS No.	134154-50-0
Molecular Formula	C15H24O2Si
Molecular Weight	264.44 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]propiophenone; 1-[3-[(tert-Butyldimethylsilyl)oxy]phenyl]-1-propanone; TBDMS Protected 3-Propionylphenol; tert-Butyldimethyl(3-propionylphenoxy)silane; 3-Propionylphenol TBDMS Ether; 3'-Hydroxypropiophenone TBDMS Ether; TBDMS-3-Propionylphenol; 3-(tert-Butyldimethylsilyloxy)propiophenone
EINECS	Contact for details

Quality Control

Our T-Butyl-Dimethylsilyl-(3-Propionylphenol) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.