Description

Bicyclo[3.2.1]Octane-3-Carbonitrile, 3-Amino-, Exo- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic scaffold and functional nitrile and amino groups. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel, complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used in lead optimization and scaffold-hopping strategies to improve drug-like properties such as potency and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for developing new pesticides and herbicides with unique modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Asymmetric Synthesis: The rigid bicyclic structure and chiral centers make it a valuable chiral auxiliary or starting material for stereoselective synthesis.
• Material Science Research: Potential precursor for specialty polymers or ligands in catalyst systems due to its strained ring system.

Basic Information

Product Name	Bicyclo[3.2.1]Octane-3-Carbonitrile, 3-Amino-, Exo- (9Ci)
CAS No.	134047-47-5
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	3-Amino-exo-bicyclo[3.2.1]octane-3-carbonitrile; exo-3-Aminobicyclo[3.2.1]octane-3-carbonitrile; Bicyclo[3.2.1]octane-3-carbonitrile, 3-amino-, exo-; 3-Amino-3-cyanobicyclo[3.2.1]octane (exo-); 134047-47-5; (1R,2S,5S,6S)-6-Amino-2-cyanobicyclo[3.2.1]octane; (exo)-3-Aminobicyclo[3.2.1]octane-3-carbonitrile
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.1]Octane-3-Carbonitrile, 3-Amino-, Exo- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (Chiral HPLC)	≥ 98.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.