Description

Trimethoxyphosphorane is a highly versatile organophosphorus reagent, primarily valued for its role as a key building block in the synthesis of complex phosphorus-containing compounds. Its high reactivity makes it an essential intermediate for advanced chemical manufacturing. This product is critical for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphate esters or phosphonate groups.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, insecticides, and plant growth regulators that utilize phosphorus chemistry.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized phosphine ligands and organometallic catalysts used in cross-coupling reactions.
• Flame Retardant Production: An intermediate in the production of certain organophosphate flame retardants and plasticizers.
• Material Science Research: Employed in the development of novel polymers, coatings, and electronic materials with tailored properties.
• Laboratory Reagent: Used in academic and industrial R&D for method development and the synthesis of novel organophosphorus compounds.

Basic Information

Product Name	Trimethoxyphosphorane
CAS No.	133930-63-9
Molecular Formula	C3H9O3P
Molecular Weight	124.08 g/mol
Synonyms	Phosphorous Acid Trimethyl Ester; Trimethyl Phosphite; Methyl Phosphite; Trimethoxyphosphine; P(OCH3)3; TMP; Trimethyl Phosphonate (common misnomer)
EINECS	Contact for details

Quality Control

Our Trimethoxyphosphorane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy, to verify identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.05 g/cm³
Boiling Point	~110-112°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.