Description

2-Tosyl-2,3,3A,4-Tetrahydrocyclopenta[C]Pyrrol-5(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring structure. This compound is of significant value in organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research and development for constructing complex polycyclic frameworks found in natural products and bioactive molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic effects.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	2-Tosyl-2,3,3A,4-Tetrahydrocyclopenta[C]Pyrrol-5(1H)-One
CAS No.	133886-43-8
Molecular Formula	C14H15NO3S
Molecular Weight	277.34 g/mol
Synonyms	2-(4-Methylphenyl)sulfonyl-2,3,3a,4-tetrahydro-1H-cyclopenta[c]pyrrol-5-one; 2-(p-Toluenesulfonyl)-2,3,3a,4-tetrahydro-1H-cyclopenta[c]pyrrol-5-one; 2-Tosyl-2,3,3a,4-tetrahydro-1H-cyclopenta[c]pyrrol-5-one; 1H-Cyclopenta[c]pyrrol-5-one, 2,3,3a,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-; 133886-43-8; Tosyl-tetrahydrocyclopentapyrrolone
EINECS	Contact for details

Quality Control

Our production of 2-Tosyl-2,3,3A,4-Tetrahydrocyclopenta[C]Pyrrol-5(1H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.