Description

2-Thiophenecarboxamide,n-Hydroxy-n-Methyl-(9Ci) is a specialized heterocyclic building block featuring a hydroxamic acid moiety. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly those designed as enzyme inhibitors. It is primarily needed by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs. Its unique structure makes it a versatile synthon for creating potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting metalloenzymes like histone deacetylases (HDACs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop and optimize new chemical entities with potential therapeutic effects.
• Biochemical Tool Compound: Acts as a precursor or reference standard in the development of biochemical assays for enzyme inhibition studies.
• Organic Synthesis: Employed as a versatile synthon in academic and industrial research for constructing complex thiophene-containing heterocycles.
• Agrochemical Development: Potential use as an intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	2-Thiophenecarboxamide,n-Hydroxy-n-Methyl-(9Ci)
CAS No.	133808-08-9
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	N-Hydroxy-N-methyl-2-thiophenecarboxamide; N-Methyl-N-hydroxy-2-thiophenecarboxamide; 2-Thiophenecarboxylic acid, N-hydroxy-N-methylamide; N-Hydroxy-N-methylthiophene-2-carboxamide; Methylhydroxamic acid, 2-thienyl-; 2-Thienyl-N-methylhydroxamic acid
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxamide,n-Hydroxy-n-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided and available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.