Description

5-Trifluoromethyl-1,3-Dihydro-Benzimidazol-2-One is a high-value, fluorinated benzimidazolone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is prized for its unique trifluoromethyl group, which imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals with specific electronic or optical properties.
• Organic Synthesis: A versatile reagent for introducing the benzimidazolone scaffold and trifluoromethyl moiety into complex molecular architectures.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme inhibition and receptor binding mechanisms.

Basic Information

Product Name	5-Trifluoromethyl-1,3-Dihydro-Benzimidazol-2-One
CAS No.	133687-93-1
Molecular Formula	C8H5F3N2O
Molecular Weight	202.13 g/mol
Synonyms	5-(Trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Trifluoromethyl-2-benzimidazolinone; 2H-Benzimidazol-2-one, 1,3-dihydro-5-(trifluoromethyl)-; 5-Trifluoromethylbenzimidazolone; 5-CF3-BIM; 133687-93-1; 5-Trifluoromethyl-2-benzimidazolone
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-1,3-Dihydro-Benzimidazol-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.