Description

2-(n-(2-Propynyl)-Aminomethyl)-1-Methyl-5-Hydroxyindole is a specialized indole derivative with a propargylamine functional group, making it a valuable synthetic intermediate for advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex molecular architectures. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and high-value biochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for the development of new chemical entities with potential therapeutic activity.
• Biochemical Probe Synthesis: Employed in the creation of labeled compounds or probes for studying biological pathways and enzyme interactions.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-purity, complex organic molecules for specialized industrial applications.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis projects and methodological development.

Basic Information

Product Name	2-(n-(2-Propynyl)-Aminomethyl)-1-Methyl-5-Hydroxyindole
CAS No.	133681-83-1
Molecular Formula	C14H16N2O
Molecular Weight	228.29 g/mol
Synonyms	1-Methyl-5-hydroxy-2-[(2-propyn-1-ylamino)methyl]indole; 2-[(2-Propynylamino)methyl]-1-methyl-5-hydroxyindole; 5-Hydroxy-1-methyl-2-[(2-propynylamino)methyl]indole; 2-(N-Propargylaminomethyl)-1-methyl-5-hydroxyindole; Propargylaminomethyl hydroxyindole derivative; CAS 133681-83-1
EINECS	Contact for details

Quality Control

Our 2-(n-(2-Propynyl)-Aminomethyl)-1-Methyl-5-Hydroxyindole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.