Description

1-[5-(3-Hydroxyprop-1-Ynyl)-2-Thienyl]Ethan-1-One is a specialized organic compound featuring a thiophene core functionalized with a hydroxyalkyne group and an acetyl moiety, making it a valuable synthetic intermediate. This compound matters for its role as a key building block in the synthesis of complex heterocyclic molecules and advanced pharmaceutical ingredients. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing thiophene or acetylene pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the thienyl-acetylene structure imparts specific biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Sonogashira, Suzuki) and cyclization reactions to create complex heterocyclic compounds for material science.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of conductive polymers or organic semiconductors due to the conjugated system of the thiophene and alkyne.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, leveraging its reactive functional groups for bioconjugation.

Basic Information

Product Name	1-[5-(3-Hydroxyprop-1-Ynyl)-2-Thienyl]Ethan-1-One
CAS No.	133665-85-7
Molecular Formula	C9H8O2S
Molecular Weight	180.22 g/mol
Synonyms	1-[5-(3-Hydroxy-1-propynyl)-2-thienyl]ethanone; 1-[5-(3-Hydroxyprop-1-yn-1-yl)thiophen-2-yl]ethan-1-one; 2-Acetyl-5-(3-hydroxy-1-propynyl)thiophene; 5-(3-Hydroxy-1-propynyl)-2-acetylthiophene; Ethanone, 1-[5-(3-hydroxy-1-propynyl)-2-thienyl]-; 3-Hydroxy-1-(5-acetyl-2-thienyl)-1-propyne
EINECS	Contact for details

Quality Control

Our 1-[5-(3-Hydroxyprop-1-Ynyl)-2-Thienyl]Ethan-1-One undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere if necessary to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.