Description

5-Chloro-4-Methoxythiophene-3-Carboxylic Acid is a high-purity, functionalized thiophene derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications such as active pharmaceutical ingredient (API) synthesis and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for conjugated polymers and organic electronic materials, such as organic semiconductors and OLED components.
• Fine Chemical Synthesis: An essential intermediate for creating specialized dyes, pigments, and other performance chemicals where the chloromethoxythiophene structure imparts specific properties.
• Academic & Industrial R&D: Employed in methodological chemistry research and scale-up process development for new synthetic routes.

Basic Information

Product Name	5-Chloro-4-Methoxythiophene-3-Carboxylic Acid
CAS No.	133659-14-0
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	5-Chloro-4-methoxy-3-thiophenecarboxylic acid; 3-Thiophenecarboxylic acid, 5-chloro-4-methoxy-; 4-Methoxy-5-chlorothiophene-3-carboxylic acid; 5-Chloro-4-methoxythiophene-3-carboxylate; 133659-14-0; Thiophene-3-carboxylic acid, 5-chloro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Methoxythiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.