Description

8-(3-tert-Butylamino-2-Hydroxypropoxy)-3,4-Dihydro-3-Oxo-2H-(1,4)-Benzothiazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzothiazine core structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and fine chemical industries engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) or cardiovascular disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in multi-step synthetic routes for the production of complex target molecules.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals for advanced material science applications.

Basic Information

Product Name	8-(3-tert-Butylamino-2-Hydroxypropoxy)-3,4-Dihydro-3-Oxo-2H-(1,4)-Benzothiazine
CAS No.	133647-19-5
Molecular Formula	C₁₅H₂₂N₂O₃S
Molecular Weight	310.41 g/mol
Synonyms	8-[(3-tert-Butylamino-2-hydroxypropoxy)]-3,4-dihydro-3-oxo-2H-1,4-benzothiazine; 8-(3-(tert-Butylamino)-2-hydroxypropoxy)-2H-1,4-benzothiazin-3(4H)-one; 2H-1,4-Benzothiazin-3(4H)-one, 8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-; 133647-19-5; tert-Butylamino hydroxypropoxy benzothiazinone
EINECS	Contact for details

Quality Control

Our 8-(3-tert-Butylamino-2-Hydroxypropoxy)-3,4-Dihydro-3-Oxo-2H-(1,4)-Benzothiazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.