Description

2,2'-Bioxazole, 4,4',5,5'-Tetrahydro-4,4'-Bis[(1S)-1-Methylpropyl]-, (4S,4'S)- is a high-value, stereochemically defined chiral compound, serving as a sophisticated building block in advanced organic synthesis. Its core value lies in its rigid, bioxazole scaffold and defined stereocenters, which are critical for imparting specific three-dimensional structure and functionality to target molecules. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity, enantiomerically pure intermediates for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in areas requiring specific stereochemistry for biological activity.
• Ligand Precursor: Used in the development of novel chiral ligands for asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Agrochemical Research: Employed as a building block for creating new, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties derived from its heterocyclic structure.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Item	Details
Product Name	2,2'-Bioxazole, 4,4',5,5'-Tetrahydro-4,4'-Bis[(1S)-1-Methylpropyl]-, (4S,4'S)-
CAS No.	133463-89-5
Molecular Formula	C16H28N2O2
Molecular Weight	280.41 g/mol
Synonyms	(4S,4'S)-4,4'-Bis[(1S)-1-Methylpropyl]-4,4',5,5'-tetrahydro-2,2'-bioxazole; (S,S)-2,2'-Bi(4,5-dihydrooxazole) derivative; Chiral C2-symmetric bioxazoline; (S,S)-4,4'-Di-sec-butyl-2,2'-bi-2-oxazoline; Enantiomerically pure bioxazole ligand precursor; (4S,4'S)-4,4'-Di-sec-butyl-4,4',5,5'-tetrahydro-2,2'-bioxazole
EINECS	Contact for details

Quality Control

Every batch of our 2,2'-Bioxazole derivative is produced under strict quality management protocols to ensure high enantiomeric purity and chemical integrity, critical for sensitive synthetic applications. We employ advanced analytical techniques including Chiral HPLC, NMR, and Mass Spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) documenting identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to the chiral and potentially sensitive nature of the compound, prolonged exposure to elevated temperatures, moisture, or strong light should be avoided to maintain stability and enantiomeric purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.