Description

(4-Iodophenoxy)(tert-Butyl)Dimethylsilane is a specialized organosilicon reagent featuring a protected phenoxy group. This compound matters as a versatile synthetic intermediate, enabling the selective introduction of the 4-iodophenoxy moiety in complex organic syntheses under controlled conditions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of functional organic electronic materials.
• Polymer Modification: Employed to introduce functional phenoxy groups into silicone-based or other specialty polymers.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Protecting Group Chemistry: The tert-butyldimethylsilyl (TBDMS) group protects the phenol oxygen during multi-step syntheses.
• Chemical Research & Development: A crucial reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Item	Details
Product Name	(4-Iodophenoxy)(tert-Butyl)Dimethylsilane
CAS No.	133430-99-6
Molecular Formula	C12H19IOSi
Molecular Weight	334.27 g/mol
Synonyms	4-Iodophenoxy-tert-butyldimethylsilane; tert-Butyl(4-iodophenoxy)dimethylsilane; 4-(tert-Butyldimethylsilyloxy)iodobenzene; 1-Iodo-4-[(tert-butyldimethylsilyl)oxy]benzene; TBDMS 4-iodophenyl ether; (p-Iodophenoxy)(tert-butyl)dimethylsilane; 4-Iodophenyl tert-butyldimethylsilyl ether
EINECS	Contact for details

Quality Control

Our (4-Iodophenoxy)(tert-Butyl)Dimethylsilane undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.