Description

5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride is a high-purity, specialized organic compound with the CAS number 133337-43-6, serving as a critical building block in advanced pharmaceutical and agrochemical research. Its unique molecular architecture, featuring a diazepane-sulfonyl moiety fused to an isoquinoline core, makes it a valuable intermediate for synthesizing novel bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector seeking to develop new therapeutic agents or crop protection solutions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in developing novel active ingredients for herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold or ligand in the design of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Contract Research: Essential for synthetic chemistry programs in universities and CROs (Contract Research Organizations) focused on heterocyclic chemistry.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and kilogram-scale production under cGMP conditions for clinical trial material.

Basic Information

Product Name	5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride
CAS No.	133337-43-6
Molecular Formula	C16H20N4O2S • HCl
Molecular Weight	368.88 g/mol (Free base: 332.42 g/mol)
Synonyms	5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline hydrochloride; 5-(1,4-Diazepane-1-sulfonyl)isoquinoline HCl; 1,4-Diazepane, 1-[(5-isoquinolinyl)sulfonyl]-, hydrochloride (1:1); 133337-43-6; 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline HCl; 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride Salt
EINECS	Contact for details

Quality Control

Every batch of 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.