Description

2-Bromo-5-Phenylthiazole is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its ability to act as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for researchers and process chemists in the fine chemical, pharmaceutical, and material science industries who require high-purity intermediates for coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those containing thiazole cores with therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the phenylthiazole moiety.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand Preparation: Utilized in the development of novel ligands for metal complexes used in catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	2-Bromo-5-Phenylthiazole
CAS No.	133311-51-0
Molecular Formula	C9H6BrNS
Molecular Weight	240.12 g/mol
Synonyms	2-Bromo-5-phenyl-1,3-thiazole; 5-Phenyl-2-bromothiazole; Thiazole, 2-bromo-5-phenyl-; 2-Bromo-5-phenylthiazole; 133311-51-0; 2-Brom-5-phenylthiazol; 2-Bromo-5-fenylthiazool
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Phenylthiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.