Description

Avermectin A1A, 4-(Acetylamino)-5-o-Demethyl-25-De(1-Methylpropyl)-4-Deoxy-25-(1-Methylethyl)-, (4R)- is a chemically modified derivative of the naturally occurring avermectin family, known for its potent biological activity. This compound is a critical high-purity intermediate for the synthesis of advanced agrochemicals and pharmaceuticals, offering researchers and manufacturers a reliable building block for developing next-generation products. It is primarily sought by R&D laboratories and fine chemical producers in the agrochemical and pharmaceutical sectors for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key synthetic precursor for developing new-generation, high-efficacy insecticides and acaricides.
• Pharmaceutical Research: Used as a building block in medicinal chemistry for the synthesis of novel antiparasitic and antimicrobial agents.
• Veterinary Medicine Development: Serves as an intermediate in the production of advanced endectocide formulations for animal health.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of macrocyclic lactones.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing of related compounds.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	Avermectin A1A, 4-(Acetylamino)-5-o-Demethyl-25-De(1-Methylpropyl)-4-Deoxy-25-(1-Methylethyl)-, (4R)-
CAS No.	133305-89-2
Molecular Formula	C48H72O14
Molecular Weight	873.1 g/mol
Synonyms	4''-Deoxy-4''-(acetylamino)avermectin A1a; 4''-Deoxy-4''-(acetylamino)avermectin B1a; 4''-Acetylamino-4''-deoxyavermectin A1a; 4''-Acetylamino-4''-deoxyavermectin B1a; 4''-Epimethylamino-4''-deoxyavermectin A1a derivative; Avermectin A1a 4''-(acetylamino)-4''-deoxy derivative; (4R)-4-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4-deoxy-25-(1-methylethyl)avermectin A1A
EINECS	Contact for details

Quality Control

Our Avermectin A1A derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.