Description

(1S)-2,2-Dimethyl-1-Phenylpropane-1,3-Diol CAS NO 133164-39-3 is a high-purity chiral diol building block of significant interest in advanced organic synthesis. This compound matters because its defined stereochemistry and functional groups make it a valuable precursor for constructing complex, optically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), chiral catalysts, and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used to develop and manufacture chiral ligands for metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex, high-value specialty chemicals and fragrances.
• Academic & Industrial Research: Employed in R&D for exploring new synthetic methodologies and developing new chemical entities.
• Material Science: Potential monomer or cross-linker in the development of specialized polymers with unique properties.

Basic Information

Product Name	(1S)-2,2-Dimethyl-1-Phenylpropane-1,3-Diol
CAS No.	133164-39-3
Molecular Formula	C13H20O2
Molecular Weight	208.30 g/mol
Synonyms	(S)-2,2-Dimethyl-1-phenyl-1,3-propanediol; (S)-2,2-Dimethyl-1-phenylpropane-1,3-diol; (S)-1,1-Dimethyl-3-phenyl-1,3-propanediol; (S)-HOCPh(CH3)2CH2CH2OH; (1S)-2,2-Dimethyl-1-phenylpropane-1,3-diol; (S)-Diol; Chiral neopentyl glycol derivative
EINECS	Contact for details

Quality Control

Our (1S)-2,2-Dimethyl-1-Phenylpropane-1,3-Diol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiles. Certificates of Analysis (COA) documenting identity, assay, and purity are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.