Description

6-(4-Chlorophenyl)-2,3-Dihydro-2,2-Dimethyl-7-Phenyl-1H-Pyrrolizine is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyrrolizine core structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique pyrrolizine-phenyl architecture.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and heterocyclic chemistry in university and corporate research settings.
• Precursor for Specialty Chemicals: Can be further functionalized to create more complex molecules for specialized applications in material science or agrochemical research.

Basic Information

Product Name	6-(4-Chlorophenyl)-2,3-Dihydro-2,2-Dimethyl-7-Phenyl-1H-Pyrrolizine
CAS No.	133111-56-5
Molecular Formula	C21H20ClN
Molecular Weight	321.84 g/mol
Synonyms	7-Phenyl-6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-1H-pyrrolizine; 2,3-Dihydro-2,2-dimethyl-7-phenyl-6-(4-chlorophenyl)-1H-pyrrolizine; 1H-Pyrrolizine, 2,3-dihydro-2,2-dimethyl-7-phenyl-6-(4-chlorophenyl)-; 6-(p-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine
EINECS	Contact for details

Quality Control

Our 6-(4-Chlorophenyl)-2,3-Dihydro-2,2-Dimethyl-7-Phenyl-1H-Pyrrolizine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.