Description

4(1H)-Pyrimidinethione, 2-Mercapto- (9Ci) is a specialized heterocyclic building block containing both pyrimidine and thiol functional groups. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the life sciences, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other bioactive heterocycles.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and plant growth regulators.
• Material Science: Serves as a precursor for ligands in catalysis and for creating functionalized polymers.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex pyrimidine-based scaffolds via thiol-mediated reactions.
• Bioconjugation Chemistry: The thiol group enables its use in linking molecules to proteins, peptides, or surfaces.

Basic Information

Product Name	4(1H)-Pyrimidinethione, 2-Mercapto- (9Ci)
CAS No.	133099-49-7
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	2-Mercapto-4(1H)-pyrimidinethione; 2,4-Dimercaptopyrimidine; 2,4-Pyrimidinedithiol; 4-Hydroxy-2-mercaptopyrimidine; 2-Thiouracil (tautomer); 2-Mercapto-4-pyrimidinol; 4-Pyrimidinol, 2-mercapto-; 1H-Pyrimidine-2,4-dithione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purities suitable for research and process development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are available upon request. Specifications can be aligned with cGMP or other relevant quality frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, minimize exposure to air and direct light during handling.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical)
Melting Point	Contact for details
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.