Description

4-Thiazolecarboxylicacid,2-(Trifluoromethyl)-,Ethylester(9Ci) CAS NO 133046-46-5 is a high-value trifluoromethyl-substituted thiazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity and stability imparted by the thiazole ring and the electron-withdrawing trifluoromethyl group, enabling the development of novel compounds with enhanced properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty chemicals, liquid crystals, and functional polymers requiring specific electronic or optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and as a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-Thiazolecarboxylicacid,2-(Trifluoromethyl)-,Ethylester(9Ci)
CAS No.	133046-46-5
Molecular Formula	C7H6F3NO2S
Molecular Weight	225.19 g/mol
Synonyms	Ethyl 2-(trifluoromethyl)-1,3-thiazole-4-carboxylate; 2-(Trifluoromethyl)-4-thiazolecarboxylic Acid Ethyl Ester; 4-Carbethoxy-2-trifluoromethylthiazole; 2-Trifluoromethyl-4-thiazolecarboxylic Acid Ethyl Ester; 4-Thiazolecarboxylic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-(trifluoromethyl)thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Thiazolecarboxylicacid,2-(Trifluoromethyl)-,Ethylester(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.