Description

Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)Methyl]Imidazol-5-Yl]-2-(2-Thienylmethyl)-2-Propenoate CAS NO 133040-06-9 is a high-purity, synthetic organic compound featuring a complex molecular architecture combining imidazole and thiophene moieties. This compound matters as a critical advanced intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules for medicinal chemistry applications.

Application

This specialized chemical intermediate serves key roles in advanced synthetic chemistry. Its primary applications include:

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) for new therapeutic agents due to its unique imidazole-thiophene core.
• API Development: Serves as a precursor in the development of novel Active Pharmaceutical Ingredients (APIs) with potential anti-inflammatory, antiviral, or oncological activity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Biochemical Probe Development: Useful in creating specialized probes for studying biological processes at the molecular level.
• Academic & Institutional Research: Supports cutting-edge chemical research in universities and government institutions focusing on heterocyclic chemistry.

Basic Information

Product Name	Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)Methyl]Imidazol-5-Yl]-2-(2-Thienylmethyl)-2-Propenoate
CAS No.	133040-06-9
Molecular Formula	C27H30N2O4S
Molecular Weight	478.60 g/mol
Synonyms	Methyl (2E)-3-[2-Butyl-1-[(4-methoxycarbonylphenyl)methyl]-1H-imidazol-5-yl]-2-[(thiophen-2-yl)methyl]prop-2-enoate; (E)-Methyl 3-(2-butyl-1-((4-(methoxycarbonyl)benzyl)-1H-imidazol-5-yl)-2-((thiophen-2-yl)methyl)acrylate; 133040-06-9; Propenoic acid, 3-[2-butyl-1-[(4-(methoxycarbonyl)phenyl)methyl]-1H-imidazol-5-yl]-2-[(2-thienyl)methyl]-, methyl ester, (2E)-; A complex imidazole-thiophene derivative ester.
EINECS	Contact for details

Quality Control

Our production of Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)Methyl]Imidazol-5-Yl]-2-(2-Thienylmethyl)-2-Propenoate adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), related substances, and physical characteristics are provided and traceable to the production batch. Our quality system is designed to support cGMP-compliant workflows for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is likely light-sensitive and may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to prevent potential oxidation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.