Description

3-(Methylsulfonamido)-2-Thiophenecarboxylic Acid is a high-purity, specialized organic building block featuring a thiophene core functionalized with both a carboxylic acid and a methylsulfonamide group. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and sophisticated agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the thiophene moiety contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials due to its conjugated thiophene system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical industry.

Basic Information

Product Name	3-(Methylsulfonamido)-2-Thiophenecarboxylic Acid
CAS No.	132864-57-4
Molecular Formula	C7H7NO4S2
Molecular Weight	233.26 g/mol
Synonyms	2-Thiophenecarboxylic acid, 3-[(methylsulfonyl)amino]-; 3-[(Methylsulfonyl)amino]thiophene-2-carboxylic acid; 3-(Methylsulfonylamino)thiophene-2-carboxylic acid; 3-(Methanesulfonamido)thiophene-2-carboxylic acid; 3-(N-Methylsulfamoyl)thiophene-2-carboxylic acid; 3-Methylsulfonamidothiophene-2-carboxylic Acid; 132864-57-4 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-(Methylsulfonamido)-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.