Description

3'-o-[(Dimethoxytrityl)Propyl][3-Hydroxypropyl]Disulfide is a specialized, high-purity chemical intermediate designed for advanced synthesis. This compound is critical for applications requiring precise molecular assembly and protection, particularly in the synthesis of complex oligonucleotides and other biomolecules. It is essential for research and production facilities in the pharmaceutical, biotechnology, and diagnostic industries that demand reliable, high-quality building blocks for their most sensitive processes.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor or modifier for the solid-phase synthesis of DNA and RNA strands.
• Bioconjugation: Used to introduce cleavable disulfide linkages or specific functional groups for labeling proteins, peptides, and other biomolecules.
• Prodrug Development: Serves as a versatile linker in the design of prodrugs where controlled release via disulfide bond cleavage is desired.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating smart materials with redox-responsive properties.
• Diagnostic Reagent Manufacturing: Employed in the production of probes and assay components where stable yet cleavable attachments are necessary.
• Chemical Biology Research: A valuable tool for studying cellular uptake, trafficking, and release mechanisms via disulfide chemistry.

Basic Information

Product Name	3'-o-[(Dimethoxytrityl)Propyl][3-Hydroxypropyl]Disulfide
CAS No.	132796-34-0
Molecular Formula	C31H34O5S2
Molecular Weight	550.72 g/mol
Synonyms	1,3-Propanediol, 2-[[3-[[bis(4-methoxyphenyl)phenylmethoxy]propyl]dithio]propyl ether; DMT-Propyl-SS-Propyl-OH; 3'-O-(DMT-Propyl Disulfide)-1-propanol; 3-Hydroxypropyl 3-[(4,4'-Dimethoxytrityl)oxy]propyl Disulfide; DMT Protected Hydroxypropyl Disulfide; SS-DMT Reagent; Disulfide DMT Ether
EINECS	Contact for details

Quality Control

Every batch of 3'-o-[(Dimethoxytrityl)Propyl][3-Hydroxypropyl]Disulfide is manufactured and tested under strict quality systems to ensure it meets the high-purity standards required for sensitive life science applications. Our rigorous quality testing includes advanced chromatographic and spectroscopic methods to verify identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.