Description

(7R,8As)-2-Benzyl-7-Hydroxyhexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione CAS NO 132714-97-7 is a high-purity, chiral heterocyclic compound belonging to the pyrrolopyrazine-dione class. This molecule is valued for its role as a sophisticated pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and complex molecular architectures.

Application

This specialized chemical serves as a critical component in several advanced industrial and research applications:

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Asymmetric Synthesis Building Block: Utilized in the construction of complex, stereochemically defined molecules for medicinal chemistry and catalyst development.
• Agrochemical Research: Employed in the development of new, high-efficacy active ingredients with specific biological activity.
• Peptidomimetic Studies: Serves as a constrained scaffold in the design of peptide analogs to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Used to create tool compounds for investigating enzyme function and protein-protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	(7R,8As)-2-Benzyl-7-Hydroxyhexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione
CAS No.	132714-97-7
Molecular Formula	C₁₅H₁₈N₂O₃
Molecular Weight	274.32 g/mol
Synonyms	2-Benzyl-7-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; (7R,8aS)-2-Benzyl-7-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, 2-(phenylmethyl)-hexahydro-7-hydroxy-, (7R,8aS)-; 132714-97-7; Chiral pyrrolopyrazinedione; Benzyl-hydroxy-pyrrolopyrazinedione.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a GMP-compatible quality system, with traceability and documentation paramount. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.