Description

2-(Ethoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 132589-66-3. This compound is a critical building block in the synthesis of complex organic molecules, offering precise chemical functionality for demanding research and production processes. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with tetrahydroisoquinoline scaffolds.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex heterocyclic compounds in medicinal chemistry research.
• Chemical Research & Development: Serves as a versatile reagent for exploring new synthetic pathways and developing novel chemical entities in academic and industrial labs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high structural precision and purity.
• Agrochemical Synthesis: Potential intermediate in the development of advanced crop protection agents and herbicides.
• Material Science Research: Used in the development of organic functional materials and ligands for catalysis.

Basic Information

Product Name	2-(Ethoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid
CAS No.	132589-66-3
Molecular Formula	C13H15NO4
Molecular Weight	249.26 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-[(ethoxycarbonyl)carbonyl]isoquinoline; Ethyl 1,2,3,4-tetrahydro-1-isoquinolinecarboxylate-1-carboxylic acid; 1-Carboxy-2-(ethoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; 2-Carbethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid, 2-(ethoxycarbonyl)-; 132589-66-3; 2-(Ethoxycarbonyl)-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Ethoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.