Description

3-Fluoro-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and research interest. Its value lies in its role as a key synthetic precursor for the development of novel therapeutic agents targeting inflammation and pain. This compound is essential for pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of novel NSAID candidates and other therapeutic molecules.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: A critical precursor in multi-step synthetic routes for target API manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating cyclooxygenase (COX) enzyme inhibition mechanisms.

Basic Information

Product Name	3-Fluoro-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid
CAS No.	132483-34-2
Molecular Formula	C₁₃H₁₀FNO₂S
Molecular Weight	263.29 g/mol
Synonyms	3-Fluoro-α-methyl-4-(thiazol-2-yl)benzeneacetic acid; 2-[3-Fluoro-4-(1,3-thiazol-2-yl)phenyl]propanoic acid; Flumizole intermediate; α-Methyl-3-fluoro-4-(2-thiazolyl)benzeneacetic acid; 4-(2-Thiazolyl)-α-methyl-3-fluorobenzenacetic acid; 2-(3-Fluoro-4-(thiazol-2-yl)phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.