Description

(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane is a high-purity, chiral bicyclic diamine building block of significant importance in advanced organic synthesis. This compound serves as a critical precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and chiral ligands. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce rigid, nitrogen-containing scaffolds with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and neurological agents.
• Catalyst & Ligand Synthesis: Used to construct sophisticated chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Agrochemical Research: Employed in developing new generations of herbicides and pesticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Functions as a versatile scaffold for designing molecular probes and enzyme inhibitors.
• Material Science: A monomer or cross-linking agent for synthesizing novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane
CAS No.	132339-20-9
Molecular Formula	C5H10N2
Molecular Weight	98.15 g/mol
Synonyms	(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane; (1S,4S)-2,5-Diazanorbornane; (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane; endo-2,5-Diazabicyclo[2.2.1]heptane; (1S,4S)-1,4-Diaminocyclopentane-2,3-diene (tautomer); DAB-H; (1S,4S)-DABCO derivative
EINECS	Contact for details

Quality Control

Our (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.