Description

5-Amino-Indan-1-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its indane carboxylic acid ester backbone with an amino functional group. This compound is crucial for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of central nervous system (CNS) active drugs and other therapeutic compounds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel drug discovery.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex indane-based molecular frameworks.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	5-Amino-Indan-1-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	132205-73-3
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	Methyl 5-aminoindane-1-carboxylate hydrochloride; 1H-Indene-1-carboxylic acid, 2,3-dihydro-5-amino-, methyl ester, hydrochloride; 5-Aminoindan-1-carboxylic acid methyl ester HCl; Methyl 5-amino-2,3-dihydro-1H-indene-1-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-Indan-1-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.