Description

4-Fluorothiophenol Potassium Salt is a versatile organosulfur building block and nucleophile, essential for advanced chemical synthesis. Its primary value lies in its role as a key intermediate for introducing the 4-fluorophenylthio moiety into complex molecular architectures. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the fluorine atom and thiophenol group contribute to efficacy and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functional polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: Acts as a nucleophilic coupling partner in various palladium-catalyzed reactions (e.g., with aryl halides) to form C-S bonds.
• Chemical Research: A valuable reagent for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	4-Fluorothiophenol Potassium Salt
CAS No.	132130-83-7
Molecular Formula	C6H4FKS
Molecular Weight	166.26 g/mol
Synonyms	Potassium 4-Fluorobenzenethiolate; Potassium 4-Fluorothiophenolate; 4-Fluorobenzenethiol Potassium Salt; p-Fluorothiophenol Potassium Salt; 4-Fluorophenylthiol Potassium Salt; Potassium p-Fluorothiophenoxide; 4-Fluoro-benzenethiolate potassium; Potassium (4-fluorophenyl)thiolate
EINECS	Contact for details

Quality Control

Our 4-Fluorothiophenol Potassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical and pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.