Description

4,4'-Dipyridyl-D8 is a deuterated isotopologue of the classic organic compound 4,4'-bipyridine, where eight hydrogen atoms are replaced with deuterium (CAS NO 132125-39-4). This isotopic labeling is critical for applications requiring non-radioactive tracing, internal standards, and mechanistic studies where hydrogen/deuterium exchange must be monitored. It is an essential research chemical for scientists in pharmaceutical development, analytical chemistry, and materials science who require high isotopic purity and structural integrity for advanced spectroscopic and kinetic investigations.

Application

• Internal Standard for Mass Spectrometry: Used as a quantitative reference standard in LC-MS and GC-MS analysis for pharmacokinetic and metabolomic studies.
• Mechanistic Probe: Employed in reaction mechanism elucidation, particularly in studies involving hydrogen/deuterium exchange (H/D exchange) and kinetic isotope effects.
• Pharmaceutical Research: Serves as a deuterated building block or tracer in the development and metabolic pathway analysis of new drug candidates.
• Analytical Method Development: Critical for validating analytical methods where distinguishing between labeled and unlabeled species is necessary.
• NMR Spectroscopy: Acts as a useful standard or probe in nuclear magnetic resonance studies due to its distinct deuterium signature.
• Materials Science Research: Utilized in the study of deuterated organic semiconductors, ligands in coordination chemistry, and other advanced materials.

Basic Information

Product Name	4,4'-Dipyridyl-D8
CAS No.	132125-39-4
Molecular Formula	C10D8N2
Molecular Weight	164.23 g/mol
Synonyms	4,4'-Bipyridine-d8; Dideutero-4,4'-bipyridine; 4,4'-Bipyridyl-d8; [2H8]-4,4'-Bipyridine; 4,4'-Dipyridine-d8; Deuterated 4,4'-Bipyridine; Perdeuterated 4,4'-Bipyridine
EINECS	Contact for details

Quality Control

Our 4,4'-Dipyridyl-D8 is manufactured under strict quality protocols to ensure high isotopic and chemical purity, essential for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-content), chemical purity by HPLC, and identity confirmation. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled to minimize prolonged exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.